研究结果

目标1:
Identify the key elements associated with aPCa among AA males and create SDOH-based interventions to potentially reduce the burden of aPCa among AA males

目标2:
Development of SDOH-based interventions for aPCa among AA males through community-based participatory research (CBPR)

合作者:

• 休斯顿卫理公会医院
• Sankofa研究所 & 社区工作组
• 社区谘询委员会
• PharmD实习生

• AA males have a higher incidence of PCa (168.8 per 100,000) compared to Caucasian males (95.每10万人中有3人)
• AA男性（12岁）.3%) are 更有可能 to present with a clinically advanced stage/aggressive PCa (aPCa) at diagnosis when compared to non-Hispanic Caucasians (6.3%)和西班牙裔男性（10%）.5%)
• Early screening for PCa improves chances for earlier stage diagnosis and reduces mortality but AA are less likely to have early screening performed

面积剥夺指数* (ADI)

A neighborhood with a high 面积剥夺指数 (ADI) is considered economically disadvantaged.

• AA Men living in an economically disadvantaged neighborhood were 更有可能 患aPCa
• Living in an economically disadvantaged neighborhood 可能会增加风险 of developing aPCa**

*ADI data collected through census track/Zipcode and not individual patient report

** - Hypothesis generated by our data that would need to be confirmed against the existing literature/validated in future studies

Medications: Thiazide and Thiazide-like Diuretics*#

• AA Men taking thiazide-like diuretics were 不太可能 患aPCa
• Use of thiazide-like diuretics may 保护 反对发展aPCa**

*- Medication data collected from individual patient report in medical record
#-Thiazide and thiazide-like diuretics used to treat hypertension. E.g. 氢氯噻嗪. 有时被称为“水丸”
** - Hypothesis generated by our data that would need to be confirmed against the existing literature/validated in future studies

Medications: Angiotensin 2 Receptor Antagonist*#

• AA Men taking angiotensin 2 receptor antagonists were 不太可能 患aPCa
• Use of angiotensin 2 receptor antagonists 可以保护 反对发展aPCa**

*- Medication data collected from individual patient report in medical record
#- Angiotensin 2 receptor antagonist used to treat hypertension. E.g. 氯沙坦，缬沙坦，奥美沙坦
** - Hypothesis generated by our data that would need to be confirmed against the existing literature/validated in future studies

药物：直接血管扩张剂*#

• AA Men taking direct vasodilators were 更有可能 患aPCa
• 使用直接血管扩张剂 可能会增加风险 开发aPCa**

*- Medication data collected from individual patient report in medical record
#- Direct vasodilators used to treat hypertension. E.g. 肼苯哒嗪
** - Hypothesis generated by our data that would need to be confirmed against the existing literature/validated in future studies

• Disseminating prostate cancer educational materials among their respective circle of influence
• Sign up for TSU mobile health coach to provide prostate cancer screening
• Prostate cancer education event or webinar
• Promote prostate cancer and health education events
• Donate to support We Roar Against Prostate Cancer funds